Lowe was the Supervisor of Titan base - a refuelling stop on the moon of Saturn. A space-shuttle arrived which had passed through a mysterious cloud in space, and the three crewmembers had become infected by a virus known as the Swarm. Lowe was able to evade being killed by them by hiding in a refrigerated room. The TARDIS arrived soon after as the Doctor had also become infected by the virus. Lowe was recruited when a dying shuttle pilot infected him. He donned a heavy duty visor to disguise the physical symptoms of the virus - silvery hairs and scales around the eyes. He pretended to help take the Doctor to the Bi-Al medical foundation - built into an asteroid. Here he began recruiting more staff. Prof. Marius helped the Doctor by shrinking short-lived clones of Leela and he, and injecting them into his body to find the Nucleus of the virus at source. Lowe infected Marius and had him send a clone copy of himself into the Doctor to stop the others. The clone Lowe was attacked and destroyed by anti-bodies.
The real Lowe transported the Nucleus back to Titan where tanks had been prepared for its eggs. The Doctor pushed him into one of these tanks, and then arranged for a gas explosion to destroy the base.
- Sheard is one of several actors who have appeared more than once in Doctor Who, who played Imperial officers in The Empire Strikes Back.
- As well as Lowe, his Doctor Who credits include The Ark, The Mind of Evil, Pyramids of Mars, Castrovalva and Remembrance of the Daleks.
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